Desferrioxamine and Acute Iron Poisoning

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منابع مشابه

Studies in acute iron poisoning. I. Desferrioxamine in the treatment of acute iron poisoning: clinical observations, experimental studies, and theoretical considerations.

OF ORIGINAL ARTICLE. Objective. Children with iron poisoning, and mongrel dogs studied under laboratory conditions, were evaluated to explore the safety and effectiveness of the use of desferrioxamine in acute iron intoxication as reported in the 1965 paper. Methodology. Twelve children admitted to a pediatric unit after iron ingestion were subjected to gastric lavage (10) and treatment either ...

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Desferrioxamine chelatable body iron.

Further experience with the differential ferrioxamine test (Fielding, 1965) for the measurement of body-iron chelation has led to modifications which include (1) an improved standard for the estimation of ferrioxamine, (2) simplified preparation of the test dose, (3) restriction of fluid during the test and (4) simplified methods of calculation. The principle of the test remains the same: an in...

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[Acute iron poisoning. A case report].

The ingestion of iron-containing products is a potential toxicological emergency. It is a leading cause of pediatric unintentional ingestion fatalities because some iron-containing compounds are readily available (vitamin mixtures, iron pills). Among adults, it has been described as accidental overdoses (mainly in pregnancy) and as suicidal attempts. We report a 42 years old woman, admitted due...

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Acute iron poisoning. Rescue with macromolecular chelators.

Acute iron intoxication is a frequent, sometimes life-threatening, form of poisoning. Present therapy, in severe cases, includes oral and intravenous administration of the potent iron chelator, deferoxamine. Unfortunately, high dose intravenous deferoxamine causes acute hypotension additive with that engendered by the iron poisoning itself. To obviate this problem, we have covalently attached d...

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Acute iron poisoning: clinical picture, intensive care needs and outcome.

In this retrospective study, we examined the prevalence of acute iron poisoning among children attending Pediatric Emergency service of a teaching hospital, and studied their clinical profile, treatment and outcome to define intensive care needs. During the 5 years' study period of 27125 patient visits to Pediatric Emergency, 337 (1.2%) were for accidental poisoning. Of these 21(7%) patients ha...

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ژورنال

عنوان ژورنال: BMJ

سال: 1964

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5417.1135